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GeneMate® BRCA+

With GeneMate® BRCA+ you can test whether you have a highly increased risk of breast, ovarian, or prostate cancers. Clinically relevant genes associated with a moderately increased risk of breast and ovarian cancers are not included in GeneMate® BRCA+. For a complete assessment of your breast and ovarian cancer risk, please see GeneMate® Breast & Ovarian and GeneMate® Breast, Gyn, & Colon.

Genes: BRCA1, BRCA2, PALB2

What's included

Saliva collection kit + shipping

State-of-the-art DNA analysis

Clinical interpretation

Connection to continued care (when needed)

2 895SEK

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Breast

Ovaries

Prostate

Genes and cancer types
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Who is GeneMate® BRCA+ best suited for?

Women

Men

Women with a family history of breast, ovarian, prostate, and/or pancreatic cancer.

Women who have been diagnosed with ovarian cancer or triple negative breast cancer.

Women who have been diagnosed with breast cancer with a family history of breast, ovarian, prostate, and/or pancreatic cancer.

Not all cancers need to present in the family in order to suspect hereditary cancer. Early onset of cancer or several instances of the same or genetically related cancer types in a family increase the likelihood that it is hereditary. Women with ovarian cancer or triple negative breast cancer are recommended genetic testing despite a lack of family history.

Men with a family history of breast, ovarian, prostate, and/or pancreatic cancer.

Men who have been diagnosed with prostate or breast cancer.

Not all cancers need to present in the family in order to suspect hereditary cancer. Early onset of cancer or several instances of the same or genetically related cancer types in a family increase the likelihood that it is hereditary. Women with ovarian cancer or triple negative breast cancer are recommended genetic testing despite a lack of family history.

Recommendations for who should undergo evaluation and genetic testing for hereditary breast cancer can be found here.

Recommendations with regards to hereditary prostate cancer can be found here

What does a positive GeneMate® BRCA+ test mean for my risk?

How much your risk is increased and for which cancer(s) depends on which gene is varied, as well as your family history including age at diagnosis.

Women

Men

Women who’s GeneMate® BRCA+ test is positive have a highly increased risk of breast cancer and a moderately to highly increased risk of ovarian cancer.

Men who’s GeneMate® BRCA+ test is positive have a highly increased risk of developing prostate cancer (BRCA2) and a somewhat increased risk of breast cancer.

How can I manage my risk if my test is positive?

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Healthy carriers can take action to reduce their risk of developing cancer or to detect cancer early for a better prognosis. Which actions to take, at what age, and with which frequency varies depending on family history and which gene is varied

Women

Men

Healthy women with an increased risk of breast cancer will be offered mammography screening and MRI of the breasts, or surgical removal of the breasts with the intent of preventing breast cancer.

Healthy women with an increased risk of gynecological cancers may consider surgical removal of ovaries and fallopian tubes and/or uterus with the intent of preventing cancer in these organs.

Healthy men with an increased risk of prostate cancer (only BRCA2 variants) will be offered prostate screening in the form of PSA testing and palpation.

2 895SEK

Order