GeneMate® Prostate & Colon
| Gene | Cancer syndrome | Most common cancers associated with a risk variant in each gene |
|---|---|---|
| BRCA1 BRCA2 |
Hereditary breast amd ovarian cancer (HBOC) Hereditary prostate cancer (BRCA2) |
Breast cancer and ovarian cancer. Hereditary prostate cancer (BRCA2) |
| EPCAM MLH1 MSH2 MSH6 PMS2 |
Lynch syndrome | Colorectal cancer, uterine (endometrial) cancer, ovarian cancer, urinary tract cancer, stomach cancer, and small bowel cancer. |
| MUTYH | MUTYH-associated polyposis (MAP) | Colorectal cancer |
| APC | Familial adenomatous polyposis (FAP) | Colorectal cancer |