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GeneMate® Prostate & Colon

Test your hereditary risk prostate and colorectal cancers. GeneMate® Prostate & Colon includes all genes associated with hereditary colorectal and prostate cancer for which there are medical management recommendations.

Genes: BRCA1, BRCA2, APC, MUTYH, EPCAM, MLH1, MSH2, MSH6, PMS2

What's included

Saliva collection kit + shipping

State-of-the-art DNA analysis

Clinical interpretation

Connection to continued care (when needed)

3 495SEK

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Colorectal

Prostate

Genes and cancer types
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Who is GeneMate® Prostate & Colon best suited for?

Men with a family history of either:

  • Prostate, breast, ovarian, pancreatic, colorectal, uterine (endometrial), ovarian, urinary tract, stomach, and/or small bowel cancer
  • Thyroid, colorectal, or uterine (endometrial) cancer
  • Retinoblastoma or any other symptom related to Neurofibromatosis 1
  • Sarcoma, brain tumors, and/or adrenal cortex cancer
  • Colorectal, stomach, pancreatic, and gynecological cancer

Men who have been diagnosed with one or several of the following cancers:

  • Prostate cancer
  • Breast cancer
  • Colorectal cancer
  • Urinary tract cancer
  • Small bowel cancer

Not all cancers need to present in the family in order to suspect hereditary cancer. Early onset of cancer or several instances of the same or genetically related cancer types in a family increase the likelihood that it is hereditary. Women with ovarian cancer or triple negative breast cancer are recommended genetic testing despite a lack of family history.

What does a positive GeneMate® Prostate & Colon test mean for my risk?

How much your risk is increased and for which cancer(s) depends on which gene is varied, as well as your family history including age at diagnosis.

Men whose GeneMate® Prostate & Colon test is positive could have an increased lifetime risk for one or more of the following cancers:

Moderately to highly increased risk for prostate cancer (BRCA2 or MSH2)

Moderately to highly increased risk for colorectal cancer (Lynch genes, MUTYH, APC)

In some cases, risk may also be increased for other cancers including urinary tract cancer, stomach cancer, pancreatic, and small bowel cancer

How can I manage my risk if my test is positive?

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Healthy carriers can take action to reduce their risk of developing cancer or to detect cancer early for a better prognosis. Which actions to take, at what age, and with which frequency varies depending on family history and which gene is varied

Healthy men with an increased risk of prostate cancer (if variant in BRCA2) may be offered prostate screening in the form of PSA testing and palpation.

Healthy men with an increased risk for colorectal cancer may be offered colonoscopy and/or endoscopy screening or surgical removal of the colon with the intent of preventing colon cancer.

Healthy men may also be offered additional screening for bladder and pancreatic cancer.

3 495SEK

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